Using computer analysis to find new uses for existing drugs in treating Alzheimer's disease.
Computational Drug Repurposing for AD/ADRD with Integrative Analysis of Real World Data and Biomedical Knowledge
This study is looking at how we can use existing medications in new ways to help people with Alzheimer’s and related dementias, so that patients might find better treatment options that are already available but not widely known.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11075213 on NIH RePORTER |
What this research studies
This research focuses on Alzheimer’s disease and related dementias, which affect millions of older adults. By utilizing real-world data from electronic health records and other sources, the project aims to identify existing medications that could be repurposed to treat these conditions more effectively. The approach combines advanced computational techniques with biological knowledge to generate new hypotheses and validate them through data analysis. Patients may benefit from discovering new treatment options that are already available but not yet recognized for their potential effectiveness in Alzheimer's care.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults diagnosed with Alzheimer's disease or related dementias.
Not a fit: Patients with early-stage cognitive impairment or those without a diagnosis of Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for Alzheimer's disease that are safer and more effective than current therapies.
How similar studies have performed: Previous research has shown promise in drug repurposing for neurodegenerative diseases, indicating that this approach could yield beneficial results.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Wang, Fei — Weill Medical Coll of Cornell Univ
- Study coordinator: Wang, Fei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.