Using combined cytokine therapy to help achieve lasting remission from HIV
Combined cytokine therapy for sustained HIV remission
This study is looking at how a special treatment combining immune boosters and a vaccine can help people with HIV have a stronger immune response, with the hope of reducing the virus in their bodies and possibly needing less ongoing medication.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10773095 on NIH RePORTER |
What this research studies
This research investigates the use of combined cytokine therapy and vaccination to enhance the immune response against HIV. By focusing on restoring the function of specific immune cells, such as CD8 T cells and NK cells, the study aims to reduce viral reservoirs in the body. The approach involves interrupting standard anti-retroviral therapy (ART) to evaluate the potential for sustained viral remission. Patients may benefit from improved immune function and a reduced need for continuous ART.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are currently on ART and are interested in exploring new therapeutic options.
Not a fit: Patients who are not living with HIV or those who have advanced stages of HIV/AIDS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a long-lasting remission from HIV without the need for ongoing medication.
How similar studies have performed: Other research has shown promise in enhancing immune responses against HIV, but this specific combination therapy approach is relatively novel.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Velu, Vijayakumar — Emory University
- Study coordinator: Velu, Vijayakumar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.