Using cold stored platelets to improve outcomes in trauma patients
The Therapeutic Potential of Cold Stored Platelets in Regulating Vascular Instability in Trauma
This study is looking at whether using cold stored platelets can help patients with traumatic injuries, like traumatic brain injury, by making their treatment more effective and improving recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10909765 on NIH RePORTER |
What this research studies
This research investigates the use of cold stored platelets as a potential treatment for patients suffering from traumatic injuries, particularly traumatic brain injury (TBI). The study aims to determine if storing platelets at lower temperatures can enhance their effectiveness in stabilizing blood vessels and reducing complications such as inflammation and bleeding. By comparing the effects of cold stored platelets to standard storage methods, the research seeks to improve patient survival rates and recovery outcomes. Patients receiving platelet transfusions may benefit from this innovative approach to trauma care.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced severe traumatic injuries, particularly those with traumatic brain injuries.
Not a fit: Patients with non-traumatic conditions or those who do not require platelet transfusions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved survival rates and recovery for trauma patients through enhanced platelet transfusion methods.
How similar studies have performed: Previous research has shown promising results with alternative storage methods for platelets, indicating potential for success in this novel approach.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Pati, Shibani — University of California, San Francisco
- Study coordinator: Pati, Shibani
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.