Using cognitive techniques to reduce cravings for cocaine.
Official title: Cognitive Reappraisal for Mitigating Incubation of Cocaine Cue-Reactivity
Funded at Icahn School of Medicine at Mount Sinai · NIH-10933557 · Data updated 2026-11-12
This study is looking at how a technique called cognitive reappraisal can help people recovering from cocaine addiction better handle their cravings when they see things that remind them of drugs, especially in the first six months of staying clean.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 30, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $837,812 |
| NIH project number | 5R37DA058039-02 |
| Project ID | NIH-10933557 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 12 and older who have a history of cocaine use and are currently in recovery.
✕Less likely to help
Patients who are not recovering from cocaine addiction or who have not previously used cocaine may not benefit from this research.
What this research studies
This research investigates how cognitive reappraisal, a method of changing emotional responses, can help individuals who are recovering from cocaine addiction manage their cravings. The study focuses on understanding how exposure to drug-related cues can lead to increased cravings and relapse, particularly during the first six months of abstinence. By training participants in cognitive reappraisal techniques, the research aims to reduce their emotional reactions to these cues, thereby decreasing the likelihood of relapse. Participants will undergo assessments using EEG to measure their brain responses to drug cues before and after the intervention.
Why it matters
Potential benefit: If successful, this research could significantly lower the risk of relapse in individuals recovering from cocaine addiction.
How similar studies have gone: Previous research has shown promise in using cognitive techniques to manage cravings in addiction, suggesting that this approach could be effective.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Parvaz, Muhammad Adeel — Icahn School of Medicine at Mount Sinai
- Study coordinator: Parvaz, Muhammad Adeel
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.