Using cognitive techniques to reduce cravings for cocaine.

Cognitive Reappraisal for Mitigating Incubation of Cocaine Cue-Reactivity

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-10933557

This study is looking at how a technique called cognitive reappraisal can help people recovering from cocaine addiction better handle their cravings when they see things that remind them of drugs, especially in the first six months of staying clean.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10933557 on NIH RePORTER

What this research studies

This research investigates how cognitive reappraisal, a method of changing emotional responses, can help individuals who are recovering from cocaine addiction manage their cravings. The study focuses on understanding how exposure to drug-related cues can lead to increased cravings and relapse, particularly during the first six months of abstinence. By training participants in cognitive reappraisal techniques, the research aims to reduce their emotional reactions to these cues, thereby decreasing the likelihood of relapse. Participants will undergo assessments using EEG to measure their brain responses to drug cues before and after the intervention.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 12 and older who have a history of cocaine use and are currently in recovery.

Not a fit: Patients who are not recovering from cocaine addiction or who have not previously used cocaine may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly lower the risk of relapse in individuals recovering from cocaine addiction.

How similar studies have performed: Previous research has shown promise in using cognitive techniques to manage cravings in addiction, suggesting that this approach could be effective.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.