Using cloud-based data to understand neuropsychiatric symptoms in Alzheimer's disease
Official title: Cloud-Based Big Neuroimaging Data Resource for Harmonized Research on Neuropsychiatric Symptoms in Alzheimer's Disease
Funded at Mclean Hospital · NIH-10838116 · Data updated 2026-11-12
This study is looking at how symptoms like depression and anxiety affect people with Alzheimer's disease, hoping to find better ways to help those who struggle with these feelings when regular treatments don't work.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mclean Hospital NIH-funded |
| Lab location | 1 site (Belmont, United States) |
| Project start | September 30, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $404,745 |
| NIH project number | 3RF1AG078304-01S1 |
| Project ID | NIH-10838116 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's disease who are experiencing neuropsychiatric symptoms.
✕Less likely to help
Patients without a diagnosis of Alzheimer's disease or those not exhibiting neuropsychiatric symptoms may not benefit from this research.
What this research studies
This research investigates the neuropsychiatric symptoms experienced by individuals with Alzheimer's disease, such as depression and anxiety, which often do not respond well to standard treatments. By analyzing large datasets from various studies, researchers aim to uncover the relationships between brain circuitry degeneration and these symptoms. The study employs advanced computational methods to analyze data from approximately 3,500 participants, enhancing the understanding of how these symptoms manifest and progress in Alzheimer's patients. This approach seeks to improve treatment strategies and outcomes for those affected.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for neuropsychiatric symptoms in Alzheimer's patients, improving their quality of life.
How similar studies have gone: Previous research has shown promise in using large datasets and computational methods to analyze neuropsychiatric symptoms, indicating that this approach could yield valuable insights.
Where this research is happening
-
Mclean Hospital
Belmont, United States Active
Researchers
- Principal investigator: Nickerson, Lisa D — Mclean Hospital
- Study coordinator: Nickerson, Lisa D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.