Using cell transformation to improve heart disease treatment
Harnessing endothelial cell transdifferentiation for cardiovascular therapy
This study is looking at how certain cells in your blood vessels can turn into different types of cells to help treat heart problems, and it aims to find out if this change helps deliver important genetic material to heart cells, which could lead to new ways to improve heart health and repair damage.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boise State University NIH-funded |
| Lab location | 1 site (Boise, United States) |
| Project ID | NIH-10513527 on NIH RePORTER |
What this research studies
This research investigates how endothelial cells can change into other cell types to help treat cardiovascular diseases. The team will explore whether this transformation is responsible for delivering genetic material to heart cells through a viral vector. By using advanced techniques, they aim to understand the mechanisms behind this process and identify specific areas in the body where these changes occur. This could lead to new strategies for enhancing heart health and repairing damaged tissues.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from cardiovascular diseases who may benefit from new treatment approaches.
Not a fit: Patients with non-cardiovascular conditions or those who do not have any heart-related issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that improve heart function and recovery from cardiovascular diseases.
How similar studies have performed: While the approach of using cell transdifferentiation is gaining interest, this specific application in cardiovascular therapy is relatively novel and has not been extensively tested.
Where this research is happening
Boise, United States
- Boise State University — Boise, United States (Active)
Researchers
- Principal investigator: Morrison, Brad — Boise State University
- Study coordinator: Morrison, Brad
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.