Using cell-free therapies from fat stem cells to speed skin wound healing

Cell-free regenerative approach in wound healing

['FUNDING_OTHER'] · JAMES A. HALEY VA MEDICAL CENTER · NIH-11130963

Looks at whether tiny particles from fat-derived stem cells can help adults with slow-healing or chronic skin wounds heal faster.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorJAMES A. HALEY VA MEDICAL CENTER (nih funded)
Locations1 site (TAMPA, UNITED STATES)
Trial IDNIH-11130963 on ClinicalTrials.gov

What this research studies

You would be offered a treatment made from tiny particles called exosomes that come from human fat-derived stem cells. Researchers plan to produce these exosomes in the lab and test how they affect healing when applied to damaged skin, using lab and preclinical models with the aim of moving toward patient treatments. The approach targets inflammation and tissue repair to help wounds close and reduce long-term damage. If involved, you could be asked for medical history, wound photos, and clinic follow-up visits.

Who could benefit from this research

Good fit: Ideal candidates would be adults with slow-healing or chronic skin wounds, including surgical wounds or wounds made worse by diabetes, aging, or infection.

Not a fit: People whose wounds already heal normally or who have medical issues that make experimental treatments unsafe may not receive benefit.

Why it matters

Potential benefit: If successful, this approach could help chronic wounds close faster and lower the risk of scarring or amputation.

How similar studies have performed: Early lab and animal studies of exosomes from adipose stem cells have shown promise for improving wound repair, but evidence in humans remains limited.

Where this research is happening

TAMPA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.