Using CBD to help treat heroin addiction

Translating CBD Treatment for Heroin Addiction

['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-10667485

This study is looking at whether CBD, a compound found in cannabis, can help people who are trying to overcome heroin addiction by reducing their cravings and anxiety, and it includes both animal tests and trials with people who will share how they feel after taking CBD.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-10667485 on ClinicalTrials.gov

What this research studies

This research investigates the potential of cannabidiol (CBD) as a treatment for heroin addiction. It aims to understand how CBD can reduce cravings and anxiety associated with heroin use by modulating brain systems involved in drug-seeking behavior. The study includes preclinical rodent experiments and human trials where participants receive CBD and report their cravings and anxiety levels. The goal is to find a non-stigmatizing treatment option that could help individuals struggling with opioid use disorder.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with a history of heroin use who are currently abstinent and experiencing cravings.

Not a fit: Patients who are not struggling with heroin addiction or those currently using opioids may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for individuals struggling with heroin addiction, potentially reducing cravings and relapse rates.

How similar studies have performed: Previous studies have shown promising results with CBD in reducing drug cravings and anxiety, indicating a potential for success in this approach.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.