Using cardiac MRI to assess risks for heart failure and atrial fibrillation in patients with hypertrophic cardiomyopathy.
Official title: Cardiac MR-Based Risk Stratification for Heart Failure and Atrial Fibrillation in HCM
Funded at Beth Israel Deaconess Medical Center · NIH-10847356 · Data updated 2026-11-12
This study is looking at how to better understand which people with hypertrophic cardiomyopathy (HCM) are most at risk for serious heart problems, using advanced heart imaging to help doctors make smarter choices about treatment and care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | April 15, 2021 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $675,466 |
| NIH project number | 5R01HL158098-04 |
| Project ID | NIH-10847356 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with hypertrophic cardiomyopathy, particularly those experiencing symptoms related to heart failure or atrial fibrillation.
✕Less likely to help
Patients without a diagnosis of hypertrophic cardiomyopathy or those who do not exhibit symptoms of heart failure or atrial fibrillation may not benefit from this research.
What this research studies
This research focuses on hypertrophic cardiomyopathy (HCM), a genetic heart disease that can lead to serious complications like heart failure and atrial fibrillation. By utilizing advanced cardiac MRI imaging, the study aims to identify which HCM patients are at the highest risk for these conditions. The approach involves analyzing heart structure and function to develop better risk stratification methods. This could help in making informed decisions about preventive treatments and management strategies for affected patients.
Why it matters
Potential benefit: If successful, this research could lead to improved risk assessment and management strategies for patients with hypertrophic cardiomyopathy, potentially reducing the incidence of heart failure and atrial fibrillation.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for risk stratification in cardiac conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Beth Israel Deaconess Medical Center
Boston, United States Active
Researchers
- Principal investigator: Nezafat, Reza — Beth Israel Deaconess Medical Center
- Study coordinator: Nezafat, Reza
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.