Using cardiac imaging to identify early signs of heart disease in families at risk
Precision Medicine for Dilated Cardiomyopathy-Cardiac Magnetic Resonance to Identify Early Family Phenotypes
This study is looking at how special heart scans can spot early signs of dilated cardiomyopathy in family members of people who have the condition, helping to catch any changes in the heart before symptoms appear.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10895268 on NIH RePORTER |
What this research studies
This research investigates how cardiac magnetic resonance (CMR) imaging can detect early signs of dilated cardiomyopathy (DCM) in individuals who have a genetic predisposition due to family history. It focuses on first-degree relatives of DCM patients, aiming to identify myocardial tissue changes before the disease manifests. By analyzing specific imaging characteristics, the study seeks to correlate these findings with genetic variants associated with DCM, potentially allowing for earlier intervention and better management of the condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are first-degree relatives of individuals diagnosed with dilated cardiomyopathy who may carry genetic variants associated with the disease.
Not a fit: Patients without a family history of dilated cardiomyopathy or those not carrying relevant genetic variants may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and treatment of dilated cardiomyopathy, improving outcomes for at-risk individuals.
How similar studies have performed: Previous research has shown that cardiac imaging techniques can successfully identify early myocardial changes in patients at risk for heart diseases, supporting the potential effectiveness of this approach.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Hershberger, Ray E. — Ohio State University
- Study coordinator: Hershberger, Ray E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.