Using carbon monoxide releasing polymers for health improvements
CO Releasing Organic Polymers for Biomedical Applications
This study is exploring a new way to use special materials that can safely release carbon monoxide to help improve heart health and reduce inflammation, making it a potential option for people dealing with cardiovascular diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Denver (Colorado Seminary) NIH-funded |
| Lab location | 1 site (Denver, United States) |
| Project ID | NIH-10861068 on NIH RePORTER |
What this research studies
This research investigates the use of carbon monoxide (CO) releasing organic polymers to improve health outcomes, particularly in treating cardiovascular diseases and reducing inflammation. The approach involves developing materials that can safely release CO in response to specific stimuli, addressing the challenges of CO's toxicity and limited solubility. By creating these polymers, the research aims to harness the therapeutic benefits of CO while minimizing risks associated with its direct use in biological systems.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from cardiovascular diseases or conditions associated with chronic inflammation.
Not a fit: Patients who do not have cardiovascular diseases or chronic inflammatory conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that effectively manage cardiovascular diseases and reduce inflammation in patients.
How similar studies have performed: While the use of carbon monoxide in therapy is a developing field, the approach of using CO releasing polymers is relatively novel and has not been extensively tested in clinical settings.
Where this research is happening
Denver, United States
- University of Denver (Colorado Seminary) — Denver, United States (Active)
Researchers
- Principal investigator: Worrell, Brady — University of Denver (Colorado Seminary)
- Study coordinator: Worrell, Brady
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.