Using cannabidiol to treat alcoholic liver disease

Cannabidiol as a treatment for alcoholic liver disease

NIH-funded research University of Louisville · NIH-10753729

This study is looking at whether taking cannabidiol (CBD), a compound from cannabis that doesn’t get you high, can help protect the liver from damage caused by drinking alcohol, and it's aimed at people who have alcoholic liver disease.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Louisville NIH-funded
Lab location1 site (Louisville, United States)
Project IDNIH-10753729 on NIH RePORTER

What this research studies

This research investigates the potential of cannabidiol (CBD), a non-psychoactive compound from cannabis, as a treatment for alcoholic liver disease (ALD). The study aims to determine if CBD can be effectively administered orally to provide protective effects against liver damage caused by alcohol consumption. Researchers will explore the underlying mechanisms of how CBD interacts with specific receptors in the intestines and its impact on liver health. By examining these effects, the research seeks to identify both therapeutic and preventive benefits of CBD for patients with ALD.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with alcoholic liver disease who may benefit from new treatment options.

Not a fit: Patients with liver disease not related to alcohol consumption may not receive benefits from this research.

Why it matters

Potential benefit: If successful, this research could offer a new oral treatment option for patients suffering from alcoholic liver disease.

How similar studies have performed: While CBD has shown promise in animal models for various conditions, this specific application for alcoholic liver disease is novel and has not been extensively tested in humans.

Where this research is happening

Louisville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.