Using butyrate therapy to improve symptoms in Gulf War veterans
Official title: Microbiome targeted oral butyrate therapy in Gulf War multisymptom illness
Funded at Veterans Health Administration · NIH-11046533 · Data updated 2026-11-12
This study is looking at how butyrate therapy might help veterans with Gulf War Illness feel better by improving their gut health and overall well-being, especially if they have tummy troubles or memory issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Long Beach, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| NIH project number | 5I01CX002372-03 |
| Project ID | NIH-11046533 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are veterans who have been diagnosed with Gulf War Illness and are experiencing related symptoms.
✕Less likely to help
Patients who do not have Gulf War Illness or those with other unrelated chronic conditions may not benefit from this research.
What this research studies
This research investigates the potential of butyrate therapy to alleviate symptoms associated with Gulf War Illness (GWI) in veterans. It focuses on understanding how the gut microbiome influences the health of these individuals, particularly in relation to gastrointestinal disturbances and cognitive function. By analyzing the microbiome and its metabolites, the study aims to restore a healthy gut environment and improve overall quality of life for affected veterans. The approach includes preclinical studies that have shown promising results in reducing inflammation and improving gut health.
Why it matters
Potential benefit: If successful, this research could provide a novel treatment option that significantly improves the quality of life for veterans suffering from Gulf War Illness.
How similar studies have gone: Other research has shown success with microbiome-targeted therapies in similar gastrointestinal and inflammatory conditions, suggesting a promising avenue for treatment.
Where this research is happening
-
Veterans Health Administration
Long Beach, United States Active
Researchers
- Principal investigator: Chatterjee, Saurabh — Veterans Health Administration
- Study coordinator: Chatterjee, Saurabh
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.