Using brain wave monitoring to improve recovery from severe brain injuries
Official title: ELECTRO-BOOST: Electroencephalography for cerebral trauma recovery and oxygenation
Funded at Yale University · NIH-10689712 · Data updated 2026-11-12
This study is looking at how certain brain activity patterns in people with severe brain injuries might affect their recovery, with the goal of finding better ways to treat and help them heal.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | August 1, 2020 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $607,200 |
| NIH project number | 5R01NS117904-04 |
| Project ID | NIH-10689712 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced severe traumatic brain injuries and exhibit signs of electrographic seizures or high-frequency periodic discharges.
✕Less likely to help
Patients with mild brain injuries or those who do not exhibit electrographic seizures or high-frequency periodic discharges may not benefit from this research.
What this research studies
This research investigates the role of electrographic seizures and high-frequency periodic discharges in patients with severe traumatic brain injuries. By monitoring brain activity, the study aims to determine if these electrical patterns are linked to worsening brain conditions and whether they can be treated effectively. The approach involves analyzing a large group of patients to understand how these brain wave abnormalities affect recovery and to develop targeted treatment strategies. Patients may benefit from improved clinical guidelines and therapies aimed at reducing secondary brain injury.
Why it matters
Potential benefit: If successful, this research could lead to better treatment options and improved recovery outcomes for patients with severe traumatic brain injuries.
How similar studies have gone: Previous research has shown that monitoring brain activity can provide valuable insights into treatment responses in brain injury cases, suggesting a potential for success in this approach.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Gilmore, Emily — Yale University
- Study coordinator: Gilmore, Emily
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.