Using brain stimulation to treat PTSD in veterans with brain injuries
Neuromodulation as a Therapy for PTSD following Chronic TBI
['FUNDING_OTHER'] · PHILADELPHIA VA MEDICAL CENTER · NIH-10982476
This study is looking at how brain stimulation can help veterans with PTSD and memory problems after a brain injury, aiming to find new ways to ease their symptoms and improve their quality of life.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PHILADELPHIA VA MEDICAL CENTER (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-10982476 on ClinicalTrials.gov |
What this research studies
This research investigates how neuromodulation can help treat post-traumatic stress disorder (PTSD) and cognitive issues that often occur after chronic traumatic brain injury (TBI) in veterans. The study focuses on understanding the brain's limbic system, which is involved in fear responses and memory, to develop effective therapies. By exploring how TBI affects fear learning and extinction, the research aims to identify new treatment strategies that could help patients manage their symptoms better. Participants may undergo brain stimulation techniques to assess their impact on PTSD and cognitive function.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans who have experienced chronic traumatic brain injury and are dealing with PTSD or cognitive difficulties.
Not a fit: Patients who do not have a history of traumatic brain injury or those without PTSD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, effective treatments for veterans suffering from PTSD and cognitive dysfunction related to TBI.
How similar studies have performed: While there have been advances in understanding fear responses and memory in relation to TBI, this specific approach using neuromodulation for PTSD treatment is relatively novel and has not been extensively tested.
Where this research is happening
PHILADELPHIA, UNITED STATES
- PHILADELPHIA VA MEDICAL CENTER — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WOLF, JOHN ALLEN — PHILADELPHIA VA MEDICAL CENTER
- Study coordinator: WOLF, JOHN ALLEN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: axon injury