Using brain stimulation to personalize treatments for drug addiction
Official title: Bayesian neurobehavioral phenotyping: from mechanism identification to personalized neuromodulation treatments
Funded at University of Tx Md Anderson Can Ctr · NIH-10804786 · Data updated 2026-11-12
This study is looking at how a special brain stimulation technique called rTMS can be customized to help people with substance use disorders by focusing on their unique brain activity, with the hope of making their treatment more effective and improving their recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | September 15, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $408,302 |
| NIH project number | 1R61DA058276-01A1 |
| Project ID | NIH-10804786 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are smokers or individuals with substance use disorders who exhibit high reactivity to drug-related cues or low cognitive control during decision-making.
✕Less likely to help
Patients who do not have substance use disorders or those who do not respond to brain stimulation therapies may not benefit from this research.
What this research studies
This research investigates how brain stimulation techniques, specifically repetitive transcranial magnetic stimulation (rTMS), can be tailored to improve treatment outcomes for individuals struggling with substance use disorders (SUDs). By identifying specific brain activity patterns related to reward and cognitive control, the study aims to personalize rTMS interventions to enhance their effectiveness. Patients will be assessed for their brain responses to drug-related cues and decision-making processes, which will guide the customization of their treatment. The goal is to reduce variability in treatment responses and improve overall recovery from addiction.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized treatments for individuals with substance use disorders, potentially improving recovery rates.
How similar studies have gone: Previous research has shown promising results using rTMS for treating substance use disorders, indicating that this approach has potential for success.
Where this research is happening
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University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Versace, Francesco — University of Tx Md Anderson Can Ctr
- Study coordinator: Versace, Francesco
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.