Using brain stimulation to improve word retrieval in people with brain injuries

Using High Definition transcranial Direct Current Stimulation Guided by Electrophysiology and Diffusion Tensor Imaging to Treat Verbal Retrieval Deficits Secondary to Chronic Traumatic Brain Injury

NIH-funded research Beth Israel Deaconess Medical Center · NIH-11253329

This study is testing a new way to help people who have trouble finding words after a brain injury by using a special type of brain stimulation to boost language-related areas in the brain, and it aims to see how this treatment can improve their ability to speak.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBeth Israel Deaconess Medical Center NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11253329 on NIH RePORTER

What this research studies

This research investigates a new treatment for individuals experiencing word finding difficulties after a traumatic brain injury (TBI). It utilizes high-definition transcranial direct current stimulation (HD-tDCS) to enhance brain activity in specific areas responsible for language. The study will assess how this stimulation affects brain function using advanced imaging techniques and will explore the relationship between brain structure and treatment effectiveness. Patients will be monitored to evaluate improvements in their verbal retrieval abilities.

Who could benefit from this research

Good fit: Ideal candidates are individuals, both veterans and civilians, who have experienced mild to moderate traumatic brain injuries and struggle with word retrieval.

Not a fit: Patients with severe brain injuries or those who do not experience verbal retrieval deficits may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve communication abilities for patients with verbal retrieval deficits following TBI.

How similar studies have performed: Previous research has shown promising results using similar brain stimulation techniques for cognitive rehabilitation, indicating potential for success in this approach.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.