Using brain stimulation to improve sleep in Parkinson's disease
Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease: An Investigation of STN LFP Biomarkers in Sleep Dysregulation and Repair
This study is looking at how a special device that tracks brain activity during sleep can help people with Parkinson's disease get better rest by adjusting stimulation in real-time to improve sleep quality.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project ID | NIH-11285063 on NIH RePORTER |
What this research studies
This research investigates how adaptive neurostimulation can help restore sleep in patients with Parkinson's disease (PD) by focusing on brain signals related to sleep. The study utilizes a specialized device to monitor brain activity during sleep and aims to develop a system that can adjust stimulation in real-time to enhance sleep quality. By identifying specific brain patterns associated with different sleep stages, the researchers hope to create a closed-loop system that promotes restorative sleep in PD patients. This innovative approach could lead to better management of one of the most challenging non-motor symptoms of Parkinson's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who experience sleep disturbances.
Not a fit: Patients without Parkinson's disease or those who do not experience sleep-related issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve sleep quality and overall well-being for patients with Parkinson's disease.
How similar studies have performed: Previous research has shown promise in using neurostimulation techniques for various neurological conditions, suggesting potential for success in this novel application.
Where this research is happening
Omaha, United States
- University of Nebraska Medical Center — Omaha, United States (Active)
Researchers
- Principal investigator: Abosch, Aviva — University of Nebraska Medical Center
- Study coordinator: Abosch, Aviva
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.