NIH-funded research NIH-funded research

Using brain stimulation to improve sleep in Parkinson's disease

Official title: Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease: An Investigation of STN LFP Biomarkers in Sleep Dysregulation and Repair

Funded at University of Nebraska Medical Center · NIH-11285063 · Data updated 2026-11-12

This study is looking at how a special device that tracks brain activity during sleep can help people with Parkinson's disease get better rest by adjusting stimulation in real-time to improve sleep quality.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Nebraska Medical Center
NIH-funded
Lab location1 site (Omaha, United States)
Project startFebruary 17, 2025
Project endJune 30, 2026
Funding year2025
Award (this year)$126,638
NIH project number3UH3NS113769-05S1
Project IDNIH-11285063 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with Parkinson's disease who experience sleep disturbances.

Less likely to help

Patients without Parkinson's disease or those who do not experience sleep-related issues may not benefit from this research.

What this research studies

This research investigates how adaptive neurostimulation can help restore sleep in patients with Parkinson's disease (PD) by focusing on brain signals related to sleep. The study utilizes a specialized device to monitor brain activity during sleep and aims to develop a system that can adjust stimulation in real-time to enhance sleep quality. By identifying specific brain patterns associated with different sleep stages, the researchers hope to create a closed-loop system that promotes restorative sleep in PD patients. This innovative approach could lead to better management of one of the most challenging non-motor symptoms of Parkinson's disease.

Why it matters

Potential benefit: If successful, this research could significantly improve sleep quality and overall well-being for patients with Parkinson's disease.

How similar studies have gone: Previous research has shown promise in using neurostimulation techniques for various neurological conditions, suggesting potential for success in this novel application.

Where this research is happening

  • University of Nebraska Medical Center
    Omaha, United States
    Active

Researchers

  • Principal investigator: Abosch, Aviva — University of Nebraska Medical Center
  • Study coordinator: Abosch, Aviva

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.