Using brain stimulation to improve emotional regulation skills

Neurostimulation Enhanced Cognitive Restructuring for Transdiagnostic Emotional Dysregulation: A Component Analysis

NIH-funded research Duke University · NIH-10978211

This study is looking at how a gentle brain stimulation technique can help adults who have trouble managing their emotions learn better ways to cope, so they can feel more in control of their feelings.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-10978211 on NIH RePORTER

What this research studies

This research investigates how noninvasive brain stimulation can enhance training in emotion regulation for adults experiencing emotional dysregulation. Participants will undergo a session that combines cognitive restructuring techniques with repetitive transcranial magnetic stimulation (rTMS) aimed at the dorsolateral prefrontal cortex. The goal is to observe immediate changes in brain activity and behavior, helping individuals learn to manage their emotions more effectively. By understanding how different parts of the brain contribute to emotional control, the research aims to develop new treatment strategies for those struggling with emotional issues.

Who could benefit from this research

Good fit: Ideal candidates are adults over 21 years old who experience difficulties in regulating their emotions, including those with anxiety, affective disorders, or related conditions.

Not a fit: Patients who do not experience emotional dysregulation or those with severe cognitive impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide new, effective interventions for individuals with emotional dysregulation, improving their ability to manage emotions and reduce distress.

How similar studies have performed: Previous research has shown promising results using neurostimulation techniques like rTMS for various psychological conditions, suggesting potential for success in this novel application.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Affective Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.