Using brain stimulation to improve emotional regulation skills
Official title: Neurostimulation Enhanced Cognitive Restructuring for Transdiagnostic Emotional Dysregulation: A Component Analysis
Funded at Duke University · NIH-10978211 · Data updated 2026-11-12
This study is looking at how a gentle brain stimulation technique can help adults who have trouble managing their emotions learn better ways to cope, so they can feel more in control of their feelings.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | January 1, 2023 |
| Project end | October 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $657,707 |
| NIH project number | 5R01MH129302-03 |
| Project ID | NIH-10978211 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults over 21 years old who experience difficulties in regulating their emotions, including those with anxiety, affective disorders, or related conditions.
✕Less likely to help
Patients who do not experience emotional dysregulation or those with severe cognitive impairments may not benefit from this research.
What this research studies
This research investigates how noninvasive brain stimulation can enhance training in emotion regulation for adults experiencing emotional dysregulation. Participants will undergo a session that combines cognitive restructuring techniques with repetitive transcranial magnetic stimulation (rTMS) aimed at the dorsolateral prefrontal cortex. The goal is to observe immediate changes in brain activity and behavior, helping individuals learn to manage their emotions more effectively. By understanding how different parts of the brain contribute to emotional control, the research aims to develop new treatment strategies for those struggling with emotional issues.
Why it matters
Potential benefit: If successful, this research could provide new, effective interventions for individuals with emotional dysregulation, improving their ability to manage emotions and reduce distress.
How similar studies have gone: Previous research has shown promising results using neurostimulation techniques like rTMS for various psychological conditions, suggesting potential for success in this novel application.
Where this research is happening
-
Duke University
Durham, United States Active
Researchers
- Principal investigator: Neacsiu, Andrada Delia — Duke University
- Study coordinator: Neacsiu, Andrada Delia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.