Using brain stimulation to improve balance in patients with progressive supranuclear palsy

Who could benefit from this research

What this research studies

This research investigates the use of non-invasive repetitive cerebellar transcranial magnetic stimulation (rTMS) to enhance balance and reduce postural instability in individuals with progressive supranuclear palsy (PSP). The study aims to understand how stimulating the cerebellum can improve motor control and decrease the risk of falls, which are common in PSP. By focusing on early interventions, the research seeks to develop effective therapies that can help patients maintain mobility and independence. Participants will undergo rTMS sessions while their balance and postural control are monitored to assess the treatment's effectiveness.

Why it matters

Where this research is happening

• Oregon Health & Science University
  Portland, United States Active

Researchers

• Principal investigator: Dale, Marian Livingston — Oregon Health & Science University
• Study coordinator: Dale, Marian Livingston

Related research

Other NIH-funded projects on the same topics.

• Imaging brain changes over time in progressive supranuclear palsy

  This project uses repeated brain scans to track disease-related changes over time in people with progressive supranuclear palsy.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11299639

• Tau’s effect on protein production in Alzheimer’s and PSP

  This grant investigates how abnormal tau protein disrupts the way cells make proteins, which may contribute to memory problems in Alzheimer’s disease and PSP.

  NIH research University of Florida · Gainesville, United States · NIH-11215570

• Platform to try new treatments for progressive supranuclear palsy

  This project will compare three medicines for people with mild to moderate progressive supranuclear palsy to learn if they are safe and help symptoms.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11160498

• Investigating tau protein accumulation and its effects on movement in brain injuries.

  This study is looking at how repeated head injuries might lead to movement problems, like those seen in Parkinson's disease, by examining changes in the brain after someone has passed away, and it aims to find clues that could help diagnose these issues better for people affected by chronic traumatic encephalopathy (CT

  NIH research Boston University Medical Campus · Boston, United States · NIH-11085161

• Understanding walking and balance problems in a rare neurological condition.

  This study is looking at how walking and balance problems affect people with progressive supranuclear palsy (PSP) and aims to create better ways to measure these issues so that patients can receive improved care and support.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-10912445

• Investigating tau protein accumulation in the brain related to Progressive Supranuclear Palsy.

  This study is looking at how a protein called tau builds up in certain parts of the brain and how that might lead to Progressive Supranuclear Palsy (PSP), with the goal of finding early signs of the disease and better ways to diagnose and treat it.

  NIH research State University of New York at Buffalo · Amherst, United States · NIH-10795724

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.