Using brain stimulation to improve balance in patients with progressive supranuclear palsy
Cerebellar TMS for postural instability in progressive supranuclear palsy
This study is looking at a safe and painless way to use brain stimulation to help people with progressive supranuclear palsy (PSP) improve their balance and reduce the risk of falling, so they can stay active and independent for longer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-11074107 on NIH RePORTER |
What this research studies
This research investigates the use of non-invasive repetitive cerebellar transcranial magnetic stimulation (rTMS) to enhance balance and reduce postural instability in individuals with progressive supranuclear palsy (PSP). The study aims to understand how stimulating the cerebellum can improve motor control and decrease the risk of falls, which are common in PSP. By focusing on early interventions, the research seeks to develop effective therapies that can help patients maintain mobility and independence. Participants will undergo rTMS sessions while their balance and postural control are monitored to assess the treatment's effectiveness.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with progressive supranuclear palsy who experience significant balance issues.
Not a fit: Patients with other forms of parkinsonism or those who do not have balance impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve balance and reduce fall risk for patients with progressive supranuclear palsy.
How similar studies have performed: Previous research has shown promising results using brain stimulation techniques for improving motor control in various neurological conditions, suggesting potential success for this approach in PSP.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Dale, Marian Livingston — Oregon Health & Science University
- Study coordinator: Dale, Marian Livingston
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.