Using brain stimulation to help Veterans with PTSD quit smoking

Neuroimaging correlates and feasibility of transcranial magnetic stimulation (TMS) to improve smoking cessation outcomes in Veterans with comorbid PTSD

NIH-funded research Durham VA Medical Center · NIH-10873007

This study is looking at how a special treatment called rTMS can help Veterans with PTSD quit smoking by understanding how their brains react to tobacco, so they can get the support they need to stop smoking for good.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDurham VA Medical Center NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-10873007 on NIH RePORTER

What this research studies

This research investigates the use of repetitive transcranial magnetic stimulation (rTMS) to improve smoking cessation outcomes specifically in Veterans who also suffer from posttraumatic stress disorder (PTSD). By employing neuroimaging techniques, the study aims to understand the brain's response to tobacco use and how rTMS can modulate these responses to support quitting. The approach includes evaluating the effectiveness of rTMS as a treatment option, particularly for those who have been excluded from previous studies due to their psychiatric conditions. The goal is to develop a tailored intervention that addresses the unique challenges faced by this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are Veterans aged 21 and older who have PTSD and are seeking help to quit smoking.

Not a fit: Patients who do not have PTSD or are not Veterans may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for Veterans with PTSD who struggle to quit smoking.

How similar studies have performed: While rTMS has shown promise in civilian populations for smoking cessation, this approach is novel for Veterans with PTSD and has not been extensively tested in this specific group.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.