NIH-funded research R01 grant

Using brain stimulation to help reduce fatigue and improve language skills after a stroke

Official title: Pre-Frontal tDCS as a novel intervention to reduce effects of post-stroke fatigue while improving language and attention in aphasia

Funded at Syracuse University · NIH-11057160 · Data updated 2026-11-12

This study is looking at how a gentle brain stimulation technique can help people who have had a stroke feel less tired and improve their language and attention skills, making it easier for them to recover and enjoy life more.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSyracuse University
NIH-funded
Lab location1 site (Syracuse, United States)
Project startDecember 1, 2024
Project endNovember 30, 2029
Funding year2025
Award (this year)$760,283
NIH project number1R01DC021677-01A1
Project IDNIH-11057160 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who have experienced a stroke and are dealing with aphasia and post-stroke fatigue.

Less likely to help

Patients who have not had a stroke or do not experience aphasia or significant fatigue may not benefit from this research.

What this research studies

This research investigates the use of transcranial direct current stimulation (tDCS) to alleviate post-stroke fatigue while enhancing language and attention in individuals with aphasia. By applying tDCS to the dorsolateral prefrontal cortex, the study aims to improve cognitive functions and language comprehension, which are often impaired after a stroke. Participants will undergo sessions of tDCS to assess its effectiveness in boosting recovery and overall quality of life. The approach is designed to maximize the brain's ability to adapt and recover following a stroke.

Why it matters

Potential benefit: If successful, this research could significantly improve the rehabilitation process for stroke survivors by reducing fatigue and enhancing communication abilities.

How similar studies have gone: Previous studies have shown promising results with tDCS in improving cognitive functions in stroke patients, indicating potential for success in this novel application.

Where this research is happening

  • Syracuse University
    Syracuse, United States
    Active

Researchers

  • Principal investigator: Riley, Ellyn — Syracuse University
  • Study coordinator: Riley, Ellyn

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.