Using brain stimulation to help reduce cravings in people addicted to cocaine
Cognitively-enhanced tDCS of the dorsolateral prefrontal cortex to reduce craving in cocaine addiction
['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11130301
This study is exploring a new way to help people with cocaine addiction by using a gentle brain stimulation technique along with exercises to help them manage their cravings and improve self-control.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11130301 on ClinicalTrials.gov |
What this research studies
This research investigates a novel approach to treating cocaine addiction by using a technique called transcranial direct current stimulation (tDCS) on the dorsolateral prefrontal cortex, combined with cognitive training. The goal is to reduce cravings and improve self-control in individuals struggling with cocaine use disorder. Participants will undergo a series of sessions where they receive either real or sham stimulation while engaging in cognitive reappraisal exercises aimed at changing their emotional responses to drug-related cues. This study aims to provide evidence-based treatment options for a population that currently lacks FDA-approved therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cocaine use disorder who experience significant cravings and are seeking treatment.
Not a fit: Patients who are not addicted to cocaine or those with other substance use disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective new treatments for individuals suffering from cocaine addiction, helping them manage cravings and improve their chances of recovery.
How similar studies have performed: Previous studies have shown promising results using tDCS for various addiction treatments, suggesting that this approach may be effective for cocaine addiction as well.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOLDSTEIN, RITA Z — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: GOLDSTEIN, RITA Z
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: addictive disorder