Using brain stimulation to enhance hand function recovery after stroke

tDCS During Contralaterally Controlled FES for Upper Extremity Hemiplegia

['FUNDING_R01'] · CASE WESTERN RESERVE UNIVERSITY · NIH-11084503

This study is testing a new therapy that combines two techniques to help stroke patients regain better control and movement in their hands, making it easier for them to do everyday tasks.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorCASE WESTERN RESERVE UNIVERSITY (nih funded)
Locations1 site (CLEVELAND, UNITED STATES)
Trial IDNIH-11084503 on ClinicalTrials.gov

What this research studies

This research investigates a new therapy combining contralaterally controlled functional electrical stimulation (CCFES) with transcranial direct current stimulation (tDCS) to improve hand function in patients who have experienced a stroke. CCFES allows patients to control the stimulation of their hand muscles, promoting better movement and dexterity. By applying tDCS during CCFES, the study aims to enhance the brain's ability to recover and improve motor function. Patients will participate in therapy sessions where both techniques are used to maximize rehabilitation outcomes.

Who could benefit from this research

Good fit: Ideal candidates are individuals who have experienced a stroke and are dealing with impaired hand function, particularly those with chronic hemiparesis.

Not a fit: Patients who have not experienced a stroke or those with other neurological conditions unrelated to stroke may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve hand function and quality of life for stroke survivors with upper-limb hemiparesis.

How similar studies have performed: Previous clinical trials have shown that CCFES-assisted therapy improves upper-limb function, suggesting that combining it with tDCS may also yield positive results.

Where this research is happening

CLEVELAND, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.