Using brain signals to help reduce cravings in people with heroin addiction

Brain-to-brain neurofeedback during naturalistic dynamic stimuli to reduce craving in heroin addiction

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-10932929

This study is exploring a new way to help people struggling with heroin cravings by using brain training techniques, so they can learn to manage their urges better and support their recovery.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10932929 on NIH RePORTER

What this research studies

This research investigates a novel approach to help individuals with heroin use disorder manage their cravings through brain-to-brain neurofeedback. Participants will engage in real-time fMRI neurofeedback, allowing them to learn how to control their brain activity in response to drug-related cues. By training their brains to modulate these signals, the goal is to reduce cravings and support recovery during early treatment. This innovative method aims to address the heightened reactivity to drug cues that often leads to relapse.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with heroin use disorder who are in the early stages of treatment.

Not a fit: Patients who are not struggling with heroin addiction or those who are not in early treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new therapeutic tool to help individuals with heroin addiction reduce their cravings and improve their chances of recovery.

How similar studies have performed: Previous studies have shown success in using neurofeedback techniques to reduce cravings in other substance use disorders, suggesting potential for this novel approach.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.