Using brain imaging and mindfulness to help treat depression in adolescents
Official title: Targeting adolescent depression symptoms using network-based real-time fMRI neurofeedback and mindfulness meditation
Funded at Northeastern University · NIH-10813160 · Data updated 2026-11-12
This study is exploring a new way to help teenagers with depression by teaching them mindfulness techniques while they get real-time feedback on their brain activity, so they can learn to manage their thoughts and feelings better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northeastern University NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | March 21, 2023 |
| Project end | February 28, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,007,310 |
| NIH project number | 5R61MH132072-02 |
| Project ID | NIH-10813160 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 12 to 21 who are experiencing symptoms of major depressive disorder.
✕Less likely to help
Patients who are not experiencing depressive symptoms or who are outside the age range of 12 to 21 may not benefit from this research.
What this research studies
This research focuses on improving treatment for adolescent major depressive disorder (MDD) by combining real-time fMRI neurofeedback with mindfulness meditation. The approach aims to target the underlying mechanisms of depression, particularly rumination, which is a common symptom that can worsen the condition. By using brain imaging, researchers will help participants learn to manage their thoughts and emotions more effectively, potentially leading to better treatment outcomes. The study will involve adolescents practicing mindfulness techniques while receiving feedback on their brain activity, helping them to develop skills to reduce depressive symptoms.
Why it matters
Potential benefit: If successful, this research could provide adolescents with more effective tools to manage their depression and improve their overall mental health.
How similar studies have gone: Previous research has shown promising results in using mindfulness techniques to reduce symptoms of depression, indicating that this approach may be effective.
Where this research is happening
-
Northeastern University
Boston, United States Active
Researchers
- Principal investigator: Whitfield-Gabrieli, Susan — Northeastern University
- Study coordinator: Whitfield-Gabrieli, Susan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.