Using blood tests and imaging to improve liver cancer detection
Liquid biopsy and radiomics for liver cancer surveillance
This study is looking for better ways to spot liver cancer early by using new blood tests and advanced imaging, and it's for people who are at risk, especially those with cirrhosis.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10931762 on NIH RePORTER |
What this research studies
This research focuses on enhancing the early detection of hepatocellular carcinoma (HCC), a rapidly growing cancer. It aims to utilize innovative blood tests, known as liquid biopsies, alongside advanced imaging techniques like MRI to identify liver cancer at earlier stages. By collecting blood samples and clinical data from a diverse group of patients, the study seeks to improve the accuracy of current surveillance methods, which often fall short. The goal is to provide a more effective approach for monitoring patients at risk of liver cancer, particularly those with cirrhosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with cirrhosis or those at high risk for developing hepatocellular carcinoma.
Not a fit: Patients without liver disease or those who do not meet the criteria for high-risk factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of liver cancer, potentially improving survival rates for patients.
How similar studies have performed: Previous studies have shown promise in using liquid biopsies for cancer detection, but this specific approach combining blood tests and MRI for liver cancer is relatively novel.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Villanueva, Augusto — Icahn School of Medicine at Mount Sinai
- Study coordinator: Villanueva, Augusto
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.