Using bioresorbable zinc staples for surgical connections in the digestive tract
Bioresorbable Zinc Staples for Anastomoses in the Digestive Tract
['FUNDING_R01'] · STATE UNIVERSITY NEW YORK STONY BROOK · NIH-10771125
This study is looking at whether using special zinc staples instead of regular titanium staples for surgeries in the digestive tract can help reduce problems like imaging issues and growth concerns in young patients, while still keeping everything securely closed as the staples safely dissolve in the body over time.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STATE UNIVERSITY NEW YORK STONY BROOK (nih funded) |
| Locations | 1 site (STONY BROOK, UNITED STATES) |
| Trial ID | NIH-10771125 on ClinicalTrials.gov |
What this research studies
This research investigates the use of bioresorbable zinc staples as an alternative to traditional titanium staples for surgical connections in the digestive tract. The study aims to address the complications associated with permanent staples, such as interference with imaging and potential growth issues in young patients. By utilizing zinc, which is biodegradable and biocompatible, the research seeks to minimize risks like leakage, stricture, and chronic inflammation. The approach involves testing the mechanical strength and safety of zinc staples in gastrointestinal anastomoses to ensure they provide adequate closure strength while being absorbed by the body over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are young patients undergoing gastrointestinal surgeries requiring anastomoses.
Not a fit: Patients who do not require gastrointestinal surgery or are older than 11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer surgical procedures for children and reduce the need for additional surgeries to remove staples.
How similar studies have performed: Previous research has shown promise in using bioresorbable materials for surgical applications, but the specific use of zinc staples in gastrointestinal anastomoses is a novel approach.
Where this research is happening
STONY BROOK, UNITED STATES
- STATE UNIVERSITY NEW YORK STONY BROOK — STONY BROOK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHU, DONGHUI — STATE UNIVERSITY NEW YORK STONY BROOK
- Study coordinator: ZHU, DONGHUI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.