Using biomaterials to improve healing of diabetic foot ulcers
Official title: ECM biomaterials for diabetic foot ulcers
Funded at Yale University · NIH-11085184 · Data updated 2026-11-12
This study is looking at new materials that could help heal diabetic foot ulcers better by improving blood flow and tissue repair, so people with diabetes can have more effective treatments and a lower risk of serious complications.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | May 1, 2022 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $466,653 |
| NIH project number | 5R01DK132645-04 |
| Project ID | NIH-11085184 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with diabetes who are experiencing chronic foot ulcers.
✕Less likely to help
Patients without diabetes or those who do not have chronic wounds may not benefit from this research.
What this research studies
This research focuses on developing new biomaterials to enhance the healing process of diabetic foot ulcers, which are common and serious complications of diabetes. The approach involves investigating the role of specific proteins in the extracellular matrix that may hinder healing and exploring how these materials can improve blood flow and tissue repair. By understanding the underlying mechanisms of impaired healing, the research aims to create more effective treatments for patients suffering from chronic wounds. Patients may benefit from innovative therapies that could reduce the risk of amputation and improve their overall health.
Why it matters
Potential benefit: If successful, this research could lead to improved healing of diabetic foot ulcers, reducing the need for amputations and enhancing patients' quality of life.
How similar studies have gone: Previous research has shown promise in using biomaterials for wound healing, indicating that this approach may lead to significant advancements in treatment.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Kyriakides, Themis R — Yale University
- Study coordinator: Kyriakides, Themis R
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-
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-
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-
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.