Using biomaterials to help the brain heal after a stroke
Biomaterials to promote synapse formation after stroke
This study is testing a special gel that can be injected into the brain after a stroke to help heal the damaged area by encouraging new blood vessels and nerve connections, making it easier for people to recover and improve their brain function.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10784674 on NIH RePORTER |
What this research studies
This research focuses on developing injectable hydrogels that can promote the repair of brain tissue following a stroke. The team aims to deliver these hydrogels directly into the stroke-affected area of the brain to encourage the formation of new blood vessels and nerve connections. By enhancing the role of astrocytes, which are crucial for brain repair, the researchers hope to improve recovery times and overall brain function. The project will assess how these biomaterials can facilitate synapse formation and support brain recovery.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults who have experienced a stroke and are seeking innovative therapeutic options for recovery.
Not a fit: Patients who have not had a stroke or those with conditions that prevent participation in experimental treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve recovery outcomes for stroke patients.
How similar studies have performed: Previous research has shown promise in using biomaterials for brain repair, but this specific approach is novel and aims to enhance recovery timelines significantly.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Segura, Tatiana — Duke University
- Study coordinator: Segura, Tatiana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.