Using biomaterials to enhance immune responses for tissue regeneration
Biomaterials-directed regenerative immunotherapies
This study is exploring new ways to help people heal better from injuries or conditions that cause tissue loss by using special treatments that work with the immune system, so patients can recover more effectively and avoid problematic scars.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10697362 on NIH RePORTER |
What this research studies
This research focuses on improving the healing process for patients suffering from tissue loss due to trauma, congenital abnormalities, or disease. It aims to manipulate the immune system to promote better tissue repair by developing regenerative immunotherapies that engage T cells. By combining biomaterials with biological cues, the project seeks to create innovative treatments that can lead to more effective healing and reduce the formation of dysfunctional scar tissue. Patients may benefit from new therapies that enhance their body's natural healing processes.
Who could benefit from this research
Good fit: Ideal candidates include individuals with congenital defects, traumatic injuries, or conditions that result in significant tissue loss.
Not a fit: Patients with stable, non-progressive conditions that do not involve tissue loss or require regenerative therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to groundbreaking therapies that significantly improve tissue healing and recovery for patients.
How similar studies have performed: Previous research in cancer immunotherapy has shown significant success, suggesting that similar approaches in regenerative medicine could also be effective.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Elisseeff, Jennifer H — Johns Hopkins University
- Study coordinator: Elisseeff, Jennifer H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.