Using biomarkers to improve vagus nerve stimulation for heart rhythm issues
Biomarker-guided optimization of transcutaneous vagal stimulation for atrial fibrillation
This study is looking at how to make a treatment called transcutaneous vagal stimulation (tVNS) work better for people with atrial fibrillation (AF) by finding specific markers in their bodies, so they can get the best care possible.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oklahoma Hlth Sciences Ctr NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project ID | NIH-11001447 on NIH RePORTER |
What this research studies
This research investigates how to optimize transcutaneous vagal stimulation (tVNS) for patients with atrial fibrillation (AF) by identifying specific biomarkers. The study aims to understand how the autonomic nervous system influences AF and to determine the best dosing and patient selection for tVNS therapy. By analyzing the effects of tVNS on heart rhythm and autonomic tone, the researchers hope to enhance treatment outcomes for individuals suffering from AF. Patients may undergo assessments to identify suitable biomarkers that can guide their therapy.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with atrial fibrillation who may benefit from vagus nerve stimulation therapy.
Not a fit: Patients without a diagnosis of atrial fibrillation or those who do not respond to vagus nerve stimulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for patients with atrial fibrillation.
How similar studies have performed: Previous studies have shown promising results with vagus nerve stimulation in managing atrial fibrillation, indicating potential for success in this approach.
Where this research is happening
Oklahoma City, United States
- University of Oklahoma Hlth Sciences Ctr — Oklahoma City, United States (Active)
Researchers
- Principal investigator: Stavrakis, Stavros — University of Oklahoma Hlth Sciences Ctr
- Study coordinator: Stavrakis, Stavros
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.