Using bioengineered materials to heal abnormal bowel-skin connections
Healing enterocutaneous fistulas using bioengineered biomaterials
This study is looking at a new, safe material that could help heal enterocutaneous fistulas—those tricky connections between the bowel and skin—so that patients can feel better and avoid more complicated treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Arizona NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project ID | NIH-10983802 on NIH RePORTER |
What this research studies
This research investigates the use of bioengineered biomaterials to treat enterocutaneous fistulas (ECFs), which are abnormal connections between the bowel and skin that can cause severe complications. The approach focuses on developing a biocompatible, non-toxic, and durable material that can effectively close these fistulas and promote healing. By addressing the underlying issues of high discharge and infection associated with ECFs, the research aims to improve patient outcomes and reduce the need for extensive medical interventions. Patients may benefit from a new treatment option that could enhance their quality of life and reduce healthcare costs.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with enterocutaneous fistulas resulting from surgical complications.
Not a fit: Patients with fistulas not caused by surgical complications or those with other unrelated gastrointestinal issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a novel treatment option for patients suffering from enterocutaneous fistulas, significantly improving their quality of life.
How similar studies have performed: Other research has shown promise in using bioengineered materials for similar medical applications, indicating potential for success in this approach.
Where this research is happening
Scottsdale, United States
- Mayo Clinic Arizona — Scottsdale, United States (Active)
Researchers
- Principal investigator: Oklu, Rahmi — Mayo Clinic Arizona
- Study coordinator: Oklu, Rahmi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.