Using biodegradable patches to treat congenital diaphragmatic hernia

Biodegradable elastic patches for congenital diaphragmatic hernia treatment

NIH-funded research University of Texas Arlington · NIH-10667413

This study is testing new stretchy patches made from biodegradable materials to help treat congenital diaphragmatic hernia in babies, aiming to improve healing and reduce complications as the child grows.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Arlington NIH-funded
Lab location1 site (Arlington, United States)
Project IDNIH-10667413 on NIH RePORTER

What this research studies

This research focuses on developing biodegradable elastic patches to treat congenital diaphragmatic hernia (CDH), a serious birth defect where abdominal organs move into the chest due to an incomplete diaphragm. The approach involves creating patches that can grow with the child, reducing the risk of complications associated with traditional synthetic materials. By utilizing innovative materials that promote healing and growth, the research aims to improve surgical outcomes for affected children. The project will involve testing these patches in a clinical setting to evaluate their effectiveness and safety.

Who could benefit from this research

Good fit: Ideal candidates for this research are infants and children diagnosed with congenital diaphragmatic hernia requiring surgical intervention.

Not a fit: Patients with congenital diaphragmatic hernia who are not candidates for surgical repair or those with other severe comorbidities may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective treatment options for children with congenital diaphragmatic hernia.

How similar studies have performed: Previous research has shown promise in using biodegradable materials for surgical applications, indicating potential success for this novel approach.

Where this research is happening

Arlington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.