NIH-funded research R01 grant

Using biodegradable metal stents to improve heart and blood vessel treatments

Official title: Biodegradable Metal Stent Alloys for Vascular Applications

Funded at Oregon Health & Science University · NIH-11118746 · Data updated 2026-11-12

This study is looking at new types of heart stents made from materials that can safely dissolve in your body, which could help reduce complications and make heart treatments easier for patients like you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOregon Health & Science University
NIH-funded
Lab location1 site (Portland, United States)
Project startApril 12, 2023
Project endMarch 31, 2027
Funding year2025
Award (this year)$636,267
NIH project number5R01HL168696-03
Project IDNIH-11118746 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients undergoing procedures that require stenting in cardiac or peripheral arteries.

Less likely to help

Patients who do not require stenting or have contraindications for stent placement may not benefit from this research.

What this research studies

This research investigates the development of biodegradable metal stents designed to enhance treatment for cardiovascular diseases. By focusing on materials that can safely dissolve in the body, the project aims to reduce complications such as thrombosis and restenosis, which are common with traditional stents. The approach involves testing various biodegradable metals like iron, magnesium, and zinc to ensure they maintain strength and compatibility with biological tissues while degrading over time. Patients may benefit from reduced need for long-term anticoagulant therapies and improved outcomes in vascular procedures.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective stent options for patients with cardiovascular diseases.

How similar studies have gone: Initial studies on biodegradable metals for stent applications have shown promise, indicating potential for success in this area.

Where this research is happening

  • Oregon Health & Science University
    Portland, United States
    Active

Researchers

  • Principal investigator: Hinds, Monica T — Oregon Health & Science University
  • Study coordinator: Hinds, Monica T

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.