Using Azithromycin to treat severe wheezing in preschoolers visiting the emergency department
1/2: AZithromycin Therapy in Preschoolers with a Severe Wheezing Episode Diagnosed at the Emergency Department (AZ-SWED)
['FUNDING_OTHER'] · UNIVERSITY OF ARIZONA · NIH-11005024
This study is looking at whether the antibiotic Azithromycin can help young children who have severe wheezing and need emergency care, to see if it can make them feel better and help prevent future asthma issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ARIZONA (nih funded) |
| Locations | 1 site (TUCSON, UNITED STATES) |
| Trial ID | NIH-11005024 on ClinicalTrials.gov |
What this research studies
This research investigates the effectiveness of the antibiotic Azithromycin in treating preschool children who experience severe wheezing episodes and require emergency department care. The study aims to determine whether Azithromycin can reduce symptoms and improve outcomes for these children, particularly those at higher risk for bacterial infections. Participants will be randomly assigned to receive either Azithromycin or a placebo, allowing researchers to assess the medication's impact on their condition. The focus is on understanding how this treatment may help alleviate severe wheezing and potentially prevent future asthma development.
Who could benefit from this research
Good fit: Ideal candidates for this research are preschool children aged 2 to 5 years who are experiencing severe wheezing episodes and require emergency department care.
Not a fit: Patients who do not experience severe wheezing episodes or are outside the preschool age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for preschoolers suffering from severe wheezing episodes, potentially reducing hospitalizations and long-term asthma development.
How similar studies have performed: Previous studies have shown promising results with Azithromycin in outpatient settings, but this research aims to explore its effectiveness in more severe cases requiring emergency care, making it a novel approach.
Where this research is happening
TUCSON, UNITED STATES
- UNIVERSITY OF ARIZONA — TUCSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MARTINEZ, FERNANDO D — UNIVERSITY OF ARIZONA
- Study coordinator: MARTINEZ, FERNANDO D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.