Using Azithromycin to treat severe wheezing in preschoolers visiting the emergency department
2/2: AZithromycin Therapy in Preschoolers with a Severe Wheezing Episode Diagnosed at the Emergency Department (AZ-SWED)
This study is looking at whether the antibiotic Azithromycin can help young kids aged 2-5 who have severe wheezing and need to go to the emergency room, to see if it can make them feel better and improve their health, especially for those more likely to get bacterial infections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-11002732 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of the antibiotic Azithromycin in treating preschoolers aged 2-5 who experience severe wheezing episodes that require emergency department visits. The study aims to determine whether Azithromycin can reduce symptoms and improve outcomes for these children, particularly those at higher risk for bacterial infections. Participants will receive either Azithromycin or a placebo to assess the medication's impact on their condition. The research is particularly focused on understanding the role of harmful bacteria in exacerbating wheezing and asthma development in young children.
Who could benefit from this research
Good fit: Ideal candidates for this research are preschoolers aged 2-5 who are experiencing severe wheezing episodes and require emergency medical care.
Not a fit: Patients who do not experience severe wheezing or are outside the age range of 2-5 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for preschoolers experiencing severe wheezing, potentially reducing hospitalizations and long-term asthma development.
How similar studies have performed: Previous studies have shown promising results with Azithromycin in outpatient settings, but this research aims to explore its effectiveness in more severe cases requiring emergency care, making it a novel approach.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Casper, Theron C — University of Utah
- Study coordinator: Casper, Theron C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.