Using automated systems to grow and study organoids from human cells
Acquisition of an automated robotic culture system for organoid generation, maintenance, and phenotyping
This study is working on making tiny versions of human organs, called organoids, easier and cheaper to create so that researchers can better understand diseases that affect the brain, gut, heart, and kidneys, ultimately helping to improve treatments for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11102448 on NIH RePORTER |
What this research studies
This research focuses on improving the generation and maintenance of organoids, which are miniaturized versions of human organs created from human induced pluripotent stem cells (hiPSCs). By acquiring an automated robotic culture system, the project aims to standardize and streamline the processes involved in organoid production, making it easier for researchers to study various human diseases. The Organoid Hub at Emory University will utilize this technology to enhance the scalability and accessibility of organoid cultures, allowing for high-throughput production of organoids that can model conditions affecting the brain, gut, heart, and kidneys. This initiative seeks to overcome existing challenges such as variability and high costs associated with organoid research.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions related to brain, gut, cardiac, or kidney diseases.
Not a fit: Patients with conditions not related to the organ systems being studied may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more reliable and standardized organoid models that improve our understanding of human diseases and enhance drug testing.
How similar studies have performed: Other research has shown success with similar automated organoid culture systems, indicating a promising approach to enhancing organoid research.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Sloan, Steven a — Emory University
- Study coordinator: Sloan, Steven a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.