NIH-funded research R01 grant

Using artificial intelligence to improve treatment for multiple brain metastases

Official title: An artificial intelligence-driven distributed stereotactic radiosurgery strategy for multiple brain metastases management

Funded at Ut Southwestern Medical Center · NIH-10749026 · Data updated 2026-11-12

This study is testing a new AI tool to help doctors plan better treatments for patients with multiple brain tumors, aiming to make radiation therapy more effective while keeping side effects low and improving quality of life.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUt Southwestern Medical Center
NIH-funded
Lab location1 site (Dallas, United States)
Project startJanuary 1, 2019
Project endDecember 31, 2025
Funding year2024
Award (this year)$526,311
NIH project number5R01CA235723-06
Project IDNIH-10749026 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients diagnosed with multiple brain metastases who are seeking advanced treatment options.

Less likely to help

Patients with a single brain metastasis or those who are not candidates for stereotactic radiosurgery may not benefit from this research.

What this research studies

This research focuses on enhancing the treatment of multiple brain metastases (mBMs) using an artificial intelligence-driven approach. It aims to develop a treatment planning system that utilizes AI to optimize stereotactic radiosurgery (SRS), a method that delivers precise radiation to tumors while minimizing damage to surrounding healthy tissue. The study will involve clinical trials to evaluate the effectiveness of this AI system in improving treatment outcomes and preserving patients' quality of life post-treatment. By addressing the challenges of treating multiple brain tumors, this research seeks to provide a safer and more effective treatment option for patients.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment outcomes and quality of life for patients with multiple brain metastases.

How similar studies have gone: Other research has shown promise in using AI for treatment planning in various medical fields, indicating potential success for this novel approach in managing multiple brain metastases.

Where this research is happening

  • Ut Southwestern Medical Center
    Dallas, United States
    Active

Researchers

  • Principal investigator: Gu, Xuejun — Ut Southwestern Medical Center
  • Study coordinator: Gu, Xuejun

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.