NIH-funded research R21 grant

Using artificial intelligence to improve treatment decisions for skin cancer

Official title: Improving prognosis prediction and therapy selection for cutaneous squamous cell carcinomas using artificial intelligence

Funded at Dana-Farber Cancer Inst · NIH-10988558 · Data updated 2026-11-12

This study is looking at a common skin cancer called cutaneous squamous cell carcinoma (cSCC) to help doctors better predict how patients will do and choose the best treatments for them, using smart computer technology to analyze tumor information and improve care for everyone.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionDana-Farber Cancer Inst
NIH-funded
Lab location1 site (Boston, United States)
Project startAugust 1, 2024
Project endJuly 31, 2027
Funding year2024
Award (this year)$693,156
NIH project number1R21EB035247-01A1
Project IDNIH-10988558 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with cutaneous squamous cell carcinoma who may benefit from personalized treatment strategies.

Less likely to help

Patients with other types of skin cancer or those whose cSCC is already at an advanced stage may not benefit from this research.

What this research studies

This research focuses on cutaneous squamous cell carcinoma (cSCC), a common type of skin cancer, and aims to enhance how doctors predict patient outcomes and select therapies. By developing advanced artificial intelligence algorithms, the project will analyze a large dataset of cSCC tumors, including their histopathology and clinical outcomes. The AI models will help identify patients at higher risk for severe disease, allowing for more tailored and effective treatment plans while minimizing unnecessary side effects for those at lower risk.

Why it matters

Potential benefit: If successful, this research could lead to more accurate treatment decisions for patients with cutaneous squamous cell carcinoma, potentially improving survival rates and quality of life.

How similar studies have gone: Other research has shown promise in using artificial intelligence for cancer prognosis and treatment selection, indicating that this approach could be effective.

Where this research is happening

  • Dana-Farber Cancer Inst
    Boston, United States
    Active

Researchers

  • Principal investigator: Lotter, William Edward — Dana-Farber Cancer Inst
  • Study coordinator: Lotter, William Edward

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.