Using artificial intelligence to improve the safety of cancer immunotherapy

Improving safety and access to immune effector cell therapy with artificial intelligence technology

NIH-funded research University of Minnesota · NIH-11018541

This study is looking at how we can better spot early signs of cognitive issues caused by cancer immunotherapy by using a friendly AI tool that listens to your speech during phone conversations, helping us catch problems sooner and keep you healthier.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Minnesota NIH-funded
Lab location1 site (Minneapolis, United States)
Project IDNIH-11018541 on NIH RePORTER

What this research studies

This research focuses on enhancing the detection of immune effector cell-associated neurotoxicity syndrome (ICANS), a serious side effect of cancer immunotherapy. By utilizing an AI-based system called SALSA, the study aims to analyze patients' speech patterns to identify early signs of cognitive impairment associated with ICANS. This approach allows for more timely intervention, potentially preventing severe complications. Patients will engage in conversations over the phone, which will be analyzed for markers of cognitive decline.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals undergoing immunotherapy for cancer who may be at risk for developing ICANS.

Not a fit: Patients not receiving immunotherapy or those without a diagnosis of cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier detection and treatment of ICANS, improving patient outcomes and safety during cancer immunotherapy.

How similar studies have performed: Previous research has shown promise in using AI for monitoring cognitive functions, suggesting that this approach could be effective.

Where this research is happening

Minneapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions anti-cancer therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.