Using artificial intelligence to analyze patient photos for chronic graft-versus-host disease
Artificial intelligence to estimate extent of cGVHD from patient photos
This study is working on a smart computer program that can help patients with chronic graft-versus-host disease (cGVHD) by analyzing photos of their skin redness, making it easier and more affordable for them to get accurate assessments without always needing to see a doctor.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11081025 on NIH RePORTER |
What this research studies
This research aims to develop and validate an artificial intelligence (AI) system that can accurately assess skin erythema, a key biomarker for chronic graft-versus-host disease (cGVHD), from photographs taken by patients. By leveraging a large database of over 11,000 images from diverse patient populations, the study seeks to create a reliable, efficient, and cost-effective tool for evaluating cGVHD, which is a significant complication following stem cell transplants. The AI technology will be tested against expert dermatologist assessments to ensure its accuracy and effectiveness in real-world settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who have undergone allogeneic hematopoietic stem cell transplantation and are experiencing symptoms of chronic graft-versus-host disease.
Not a fit: Patients who have not undergone stem cell transplantation or do not exhibit symptoms of chronic graft-versus-host disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a more accurate and accessible method for monitoring cGVHD, leading to improved patient outcomes and treatment validation.
How similar studies have performed: Previous research has shown promise in using AI for medical assessments, indicating that this approach could lead to significant advancements in the evaluation of cGVHD.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Tkaczyk, Eric R — Vanderbilt University Medical Center
- Study coordinator: Tkaczyk, Eric R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.