Using artificial intelligence to analyze blood vessel changes in smokers with pulmonary hypertension
Official title: Structural and Funcional Vascular Phenotyping in Smokers with Pulmonary Hypertension using Artificial Intelligence
Funded at Brigham and Women's Hospital · NIH-10993682 · Data updated 2026-11-12
This study is looking at how artificial intelligence can help spot changes in the blood vessels of smokers with pulmonary hypertension, especially those with COPD, by analyzing special CT scans to find new signs of the disease, which could lead to earlier detection and better treatment outcomes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $187,320 |
| NIH project number | 5K25HL157601-02 |
| Project ID | NIH-10993682 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are smokers who have been diagnosed with pulmonary hypertension, particularly those with a history of chronic obstructive pulmonary disease.
✕Less likely to help
Patients who do not smoke or those with pulmonary hypertension not related to smoking or COPD may not benefit from this research.
What this research studies
This research investigates how artificial intelligence can help identify structural and functional changes in blood vessels of smokers suffering from pulmonary hypertension (PH). By analyzing non-contrast CT images, the study aims to uncover new markers that indicate the presence of PH, particularly in patients with chronic obstructive pulmonary disease (COPD). The goal is to enhance early detection and understanding of the disease, which is often complicated by other conditions. This approach could lead to better assessment of treatment responses and improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for smokers with pulmonary hypertension.
How similar studies have gone: Other research has shown promise in using artificial intelligence for medical imaging analysis, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Nardelli, Pietro — Brigham and Women's Hospital
- Study coordinator: Nardelli, Pietro
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.