Using an AI tool to help ER doctors decide heart-attack care for people with dementia

Project 1 - HEARTSPOT: Evaluating a Machine Learning System to Aid Decision-Making in the Emergency Department for Patients with ADRD

NIH-funded research National Bureau of Economic Research · NIH-11195561

This project will use an AI tool inside the electronic health record to give emergency doctors clearer information when deciding heart-attack care for older adults with Alzheimer's and related dementias.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionNational Bureau of Economic Research NIH-funded
Lab location1 site (Cambridge, United States)
Project IDNIH-11195561 on NIH RePORTER

What this research studies

From a patient's view, an algorithm will run within a hospital's electronic records to spot signs of acute coronary syndrome (heart attack) in people with dementia and summarize each patient's risk for the treating clinician. The tool will produce a clear decision aid at the point when emergency clinicians choose a treatment path. Its effect will be tested by turning the tool on for some emergency encounters or sites and comparing outcomes to usual care. The team hopes the algorithm fills information gaps that often make cardiac decisions harder for patients with Alzheimer's and related dementias.

Who could benefit from this research

Good fit: People with Alzheimer's disease or related dementias who come to a participating emergency department with chest pain or suspected acute coronary syndrome would be the most relevant candidates.

Not a fit: Patients without suspected cardiac problems, those treated outside the participating health system's emergency departments, or those with conditions unrelated to acute coronary syndrome are unlikely to benefit directly.

Why it matters

Potential benefit: If successful, this could help ER clinicians make safer, more accurate heart-attack treatment decisions for people with Alzheimer's and related dementias.

How similar studies have performed: Other AI risk tools and clinical decision aids in emergency medicine have shown promise, but applying such tools specifically to people with dementia is relatively new.

Where this research is happening

Cambridge, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.