NIH-funded research P01 program project

Using an AI tool to help ER doctors decide heart-attack care for people with dementia

Official title: Project 1 - HEARTSPOT: Evaluating a Machine Learning System to Aid Decision-Making in the Emergency Department for Patients with ADRD

Funded at National Bureau of Economic Research · NIH-11195561 · Data updated 2026-11-12

This project will use an AI tool inside the electronic health record to give emergency doctors clearer information when deciding heart-attack care for older adults with Alzheimer's and related dementias.

More Decision Making research and trials

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionNational Bureau of Economic Research
NIH-funded
Lab location1 site (Cambridge, United States)
Project startFebruary 1, 1997
Project endAugust 31, 2029
Funding year2025
Award (this year)$374,537
NIH project number5P01AG005842-36
Project IDNIH-11195561 on NIH RePORTER

Who could benefit from this research

Could help

People with Alzheimer's disease or related dementias who come to a participating emergency department with chest pain or suspected acute coronary syndrome would be the most relevant candidates.

Less likely to help

Patients without suspected cardiac problems, those treated outside the participating health system's emergency departments, or those with conditions unrelated to acute coronary syndrome are unlikely to benefit directly.

What this research studies

From a patient's view, an algorithm will run within a hospital's electronic records to spot signs of acute coronary syndrome (heart attack) in people with dementia and summarize each patient's risk for the treating clinician. The tool will produce a clear decision aid at the point when emergency clinicians choose a treatment path. Its effect will be tested by turning the tool on for some emergency encounters or sites and comparing outcomes to usual care. The team hopes the algorithm fills information gaps that often make cardiac decisions harder for patients with Alzheimer's and related dementias.

Why it matters

Potential benefit: If successful, this could help ER clinicians make safer, more accurate heart-attack treatment decisions for people with Alzheimer's and related dementias.

How similar studies have gone: Other AI risk tools and clinical decision aids in emergency medicine have shown promise, but applying such tools specifically to people with dementia is relatively new.

Where this research is happening

  • National Bureau of Economic Research
    Cambridge, United States
    Active

Researchers

  • Principal investigator: Baicker, Katherine — National Bureau of Economic Research
  • Study coordinator: Baicker, Katherine

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.