Using amnion cell secretome to treat traumatic brain injury

Amnion cell secretome mediated therapy for traumatic brain injury

['FUNDING_OTHER'] · JAMES A. HALEY VA MEDICAL CENTER · NIH-10932936

This study is looking at a new treatment called ST266 to see if it can help veterans who have had repeated mild brain injuries by improving their thinking, mood, and movement, while also reducing inflammation in their bodies.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorJAMES A. HALEY VA MEDICAL CENTER (nih funded)
Locations1 site (TAMPA, UNITED STATES)
Trial IDNIH-10932936 on ClinicalTrials.gov

What this research studies

This research investigates a novel treatment for traumatic brain injury (TBI) using a substance called ST266, derived from amnion cells. The study aims to understand how this treatment can help mitigate the long-term effects of repetitive mild traumatic brain injuries, particularly in veterans. By using an animal model, researchers will assess the impact of ST266 on cognitive function, anxiety, and motor skills, as well as its ability to reduce inflammation in the brain and body. The goal is to enhance the standard of care for individuals suffering from TBI.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced traumatic brain injuries, particularly veterans.

Not a fit: Patients with non-traumatic brain injuries or those who have not sustained any form of brain injury may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for veterans and others affected by traumatic brain injuries.

How similar studies have performed: Previous research has shown promise in using secretomes for neuroprotection, suggesting potential success for this novel approach.

Where this research is happening

TAMPA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired brain injury

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.