Using amnion cell secretome to treat traumatic brain injury
Official title: Amnion cell secretome mediated therapy for traumatic brain injury
Funded at James a. Haley VA Medical Center · NIH-10932936 · Data updated 2026-11-12
This study is looking at a new treatment called ST266 to see if it can help veterans who have had repeated mild brain injuries by improving their thinking, mood, and movement, while also reducing inflammation in their bodies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | James a. Haley VA Medical Center NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project start | October 1, 2023 |
| Project end | September 30, 2027 |
| Funding year | 2025 |
| NIH project number | 5I01RX004245-02 |
| Project ID | NIH-10932936 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced traumatic brain injuries, particularly veterans.
✕Less likely to help
Patients with non-traumatic brain injuries or those who have not sustained any form of brain injury may not benefit from this research.
What this research studies
This research investigates a novel treatment for traumatic brain injury (TBI) using a substance called ST266, derived from amnion cells. The study aims to understand how this treatment can help mitigate the long-term effects of repetitive mild traumatic brain injuries, particularly in veterans. By using an animal model, researchers will assess the impact of ST266 on cognitive function, anxiety, and motor skills, as well as its ability to reduce inflammation in the brain and body. The goal is to enhance the standard of care for individuals suffering from TBI.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for veterans and others affected by traumatic brain injuries.
How similar studies have gone: Previous research has shown promise in using secretomes for neuroprotection, suggesting potential success for this novel approach.
Where this research is happening
-
James a. Haley VA Medical Center
Tampa, United States Active
Researchers
- Principal investigator: Mouzon, Benoit Christian — James a. Haley VA Medical Center
- Study coordinator: Mouzon, Benoit Christian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.