Using algorithms to analyze genetic data related to brain imaging
Informatics Algorithms for Genomic Analysis of Brain Imaging Data
['FUNDING_R01'] · UNIVERSITY OF PENNSYLVANIA · NIH-10591596
This study is looking at how our genes might influence brain scans, especially for people with Alzheimer's and other mental health issues, to help improve how we diagnose and treat these conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-10591596 on ClinicalTrials.gov |
What this research studies
This research investigates how genetic variations affect brain imaging traits, particularly in the context of Alzheimer's disease and other mental health disorders. By developing new informatics strategies, the project aims to connect genetic data with brain imaging results, leveraging existing transcriptomics data to enhance understanding of these relationships. Patients may benefit from improved diagnostic and therapeutic approaches as the research seeks to identify meaningful genetic associations linked to brain health. The study will utilize large data repositories to ensure comprehensive analysis.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or those experiencing cognitive decline.
Not a fit: Patients with non-neurological conditions or those not affected by cognitive disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatments for Alzheimer's disease and related mental health disorders.
How similar studies have performed: Previous research in brain imaging genetics has shown promise, suggesting that this approach could yield significant insights into Alzheimer's disease.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHEN, LI — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: SHEN, LI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease