NIH-funded research R21 grant

Using air cleaners in schools to reduce respiratory virus exposure in children

Official title: High efficiency particulate air cleaner intervention to reduce respiratory virus exposure in elementary schools

Funded at Massachusetts General Hospital · NIH-10885171 · Data updated 2026-11-12

This study is looking at how the air quality in schools affects kids' chances of getting sick from respiratory viruses, especially for those with asthma, and will test if using special air cleaners in classrooms can help keep them healthier.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startJuly 10, 2023
Project endJune 30, 2026
Funding year2024
Award (this year)$215,387
NIH project number5R21AI178155-02
Project IDNIH-10885171 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 0-11 years, particularly those with asthma or other respiratory conditions.

Less likely to help

Patients who are older than 11 years or do not have respiratory issues may not benefit from this research.

What this research studies

This research investigates how the school environment affects children's exposure to respiratory viruses and explores ways to improve indoor air quality. The study will utilize high efficiency particulate air (HEPA) cleaners in classrooms to see if they can effectively reduce airborne viruses and the incidence of respiratory infections among elementary school children, particularly those with asthma. By comparing classrooms with and without these air cleaners, researchers aim to identify key environmental factors that contribute to virus transmission. The findings could lead to better health interventions in schools, especially in the context of ongoing respiratory virus concerns.

Why it matters

Potential benefit: If successful, this research could significantly lower the rates of respiratory infections in children, improving their overall health and school attendance.

How similar studies have gone: Previous studies have shown that HEPA air cleaners can effectively reduce airborne allergens and viruses, suggesting a promising approach for this intervention.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Lai, Peggy Sue — Massachusetts General Hospital
  • Study coordinator: Lai, Peggy Sue

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.