Using AI to Speed Up Genetic Discoveries in Mice
Enabling AI-based Mouse Genetic Discovery
This project develops advanced artificial intelligence tools to quickly find genetic causes of human diseases by studying mouse models.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11139608 on NIH RePORTER |
What this research studies
Researchers are creating a new and improved AI system, called AIv2, to analyze genetic information from laboratory mice. This system will use advanced computing and long-read genomic sequencing to create a more complete map of genetic differences in mice. By combining this genetic data with information from millions of published scientific papers and protein interactions, the AI can pinpoint specific genes linked to human health conditions. This approach aims to significantly speed up the process of identifying genetic factors that contribute to various diseases.
Who could benefit from this research
Good fit: This foundational research does not involve direct patient participation, but future patients with various genetic conditions could ultimately benefit from its discoveries.
Not a fit: Patients seeking immediate treatment or direct clinical intervention will not receive benefit from this early-stage research.
Why it matters
Potential benefit: If successful, this work could dramatically accelerate the discovery of new genetic factors and potential therapies for a wide range of human diseases.
How similar studies have performed: The researchers have previously developed an initial AI pipeline that successfully identified genetic factors in mouse models, indicating promise for this enhanced version.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Peltz, Gary a — Stanford University
- Study coordinator: Peltz, Gary a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.