NIH-funded research Career grant

Using AI to predict heart function in patients with repaired tetralogy of Fallot

Official title: Precision Prediction of Right Ventricular Size, Function, and Outcomes in Patients with Repaired Tetralogy of Fallot

Funded at Icahn School of Medicine at Mount Sinai · NIH-11055102 · Data updated 2026-11-12

This study is looking to make it easier for people who have had surgery for tetralogy of Fallot to understand their heart health by using advanced technology to analyze heart tests, so they can avoid extra MRIs and get better care.

More Tetralogy of Fallot research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai
NIH-funded
Lab location1 site (New York, United States)
Project startMarch 1, 2025
Project endFebruary 28, 2030
Funding year2025
Award (this year)$167,588
NIH project number1K08HL173639-01A1
Project IDNIH-11055102 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals aged 12 years and older who have undergone surgical repair for tetralogy of Fallot.

Less likely to help

Patients without a history of tetralogy of Fallot or those who are not within the specified age range may not benefit from this research.

What this research studies

This research focuses on improving the prediction of right ventricular size and function in patients who have undergone repair for tetralogy of Fallot, a congenital heart defect. By utilizing advanced artificial intelligence techniques, the study aims to analyze data from electrocardiograms and echocardiograms to provide more accurate risk assessments for heart failure and other complications. This approach seeks to reduce the need for frequent cardiac MRIs, which can be burdensome for patients. The ultimate goal is to enhance patient management and outcomes through better risk stratification.

Why it matters

Potential benefit: If successful, this research could lead to more accurate monitoring and management of heart health in patients with repaired tetralogy of Fallot, potentially reducing complications and improving quality of life.

How similar studies have gone: Previous research has shown promise in using AI for cardiovascular imaging and risk prediction, indicating that this approach could be effective.

Where this research is happening

  • Icahn School of Medicine at Mount Sinai
    New York, United States
    Active

Researchers

  • Principal investigator: Duong, Son Quang — Icahn School of Medicine at Mount Sinai
  • Study coordinator: Duong, Son Quang

Related research

Other NIH-funded projects on the same topics.

  • Why repaired Tetralogy of Fallot can cause heart rhythm problems and low exercise capacity

    This project looks at whether rising pressure in the right atrium leads to arrhythmias and worse exercise ability in adults who had Tetralogy of Fallot repaired.

    NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11134442

  • Using beta-blockers to help heart cells grow in children with Tetralogy of Fallot

    This study is looking at how a type of medicine called beta-blockers might help heart muscle cells grow in children with Tetralogy of Fallot, a heart condition they were born with, to better understand how to improve their heart function after surgery.

    NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11080369

  • New MRI techniques to predict heart issues in patients with tetralogy of Fallot

    This study is looking to help people who have had surgery for tetralogy of Fallot by using special heart scans to better predict serious heart problems, so doctors can know when to step in and provide the right care.

    NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11011367

  • Evaluating heart function in adults with tetralogy of Fallot

    This study is looking at how well the hearts of adults who had surgery for tetralogy of Fallot are working, using a new type of CT scan to find any problems that regular tests might miss, so we can help improve their care and health in the long run.

    NIH research University of California, San Diego · La Jolla, United States · NIH-11004602

  • Understanding heart issues in patients with repaired tetralogy of Fallot

    This study is looking at why some people who have had surgery for tetralogy of Fallot experience heart rhythm problems and trouble with exercise, and it hopes to find out if fixing a specific heart valve early on can help them feel better and live longer.

    NIH research Mayo Clinic Rochester · Rochester, United States · NIH-10908524

  • Understanding heart changes in children with Tetralogy of Fallot

    This study looks at how the hearts of children with Tetralogy of Fallot change over time, especially the right ventricle, to help doctors find out which kids might need extra care after their surgery.

    NIH research University of Pennsylvania · Philadelphia, United States · NIH-10897232

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.