Using AI to improve the effectiveness of stem cell therapies
AI-informed Signaling Factor Design for in vitro Rejuvenating Mesenchymal Stromal Cells
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11094242
This study is looking at ways to keep stem cells healthier for longer so they can work better in treating different diseases, which could lead to more effective treatments for patients like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-11094242 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the potency of mesenchymal stromal cells (MSCs) used in therapies for various diseases. It aims to prevent these cells from aging too quickly in laboratory settings by adjusting key metabolic signaling pathways. By utilizing advanced imaging technology, the project will observe and analyze the cellular processes that lead to MSC senescence, ultimately improving their therapeutic potential. Patients may benefit from more effective stem cell treatments as a result of this innovative approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that could benefit from stem cell therapies, such as degenerative diseases or injuries.
Not a fit: Patients who do not require stem cell therapies or have conditions unrelated to cellular aging may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective stem cell therapies for a range of diseases.
How similar studies have performed: Previous research has shown promise in using signaling pathway modulation to enhance stem cell potency, indicating that this approach may be effective.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIN, NEIL — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: LIN, NEIL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.